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  • Imaris allows for straightforward yet sophisticated analyses and provides the proper balance between user interaction and automation.


Michael Liebling4D Imaging of the Embryonic Zebrafish Heart DevelopmentDr. Michael Liebling is an Assistant Professor in the Department of Electrical and Computer Engineering at the University of California, Santa Barbara (UCSB) and a Visiting Associate in the Department of Biology at the California Institute of Technology in Pasadena. He received his MS in Physics (2000) and PhD in Image Processing (2004) from the École Polytechnique Fédérale de Lausanne (EPFL), Switzerland.


A major focus in Michael Liebling’s lab is the quantitative study of heart morphogenesis. More specifically, they develop novel in vivo imaging tools to follow the fate of individual cardiac cells in the beating and developing embryonic heart.

The image on the right shows 4D Imaging of the Embryonic Zebrafish Heart Development. This 80 hpf Tg(gata1:GFP) zebrafish, counterstain with Bodipy dye (in gray), was imaged on an LSM 5 LIVE confocal microscope (Zeiss) and rendered with Imaris (Data: M. Liebling and A. Forouhar).

 

Dr. Liebling says: “Imaris has been a great asset to visualize our multi-dimensional data (3D + time, multiple channels, and size that often exceeds the amount of RAM memory typically found in high-end desktop computers) and produce high-quality movies for our publications.”

“Through its sleek user interface, Imaris allows for straightforward yet sophisticated analyses and provides the proper balance between user interaction and automation.”

Most importantly he realizes that “Imaris allows us to seamlessly integrate our own specific image processing routines via ImarisXT and to leverage Imaris' strengths for generic analysis and visualization tasks. This relieves us of such major burdens as reading-in a wide range of microscopy data formats or implementing interactive graphical user interfaces and allows our team to focus on those image processing tasks specific to our research while keeping maximal flexibility towards our collaborators.”